The Wild West, circa 1870. Samuel Alabaster, an affluent pioneer, ventures across the American frontier to marry the love of his life, Penelope. As his group traverses the west, the once-simple journey grows treacherous, blurring the lines between hero, villain and damsel.
Double-crossed and left without water in the desert, Cable Hogue is saved when he finds a spring. It is in just the right spot for a much needed rest stop on the local stagecoach line, and Hogue uses this to his advantage. He builds a house and makes money off the stagecoach passengers. Hildy, a prostitute from the nearest town, moves in with him. Hogue has everything going his way until the advent of the automobile ends the era of the stagecoach.
The Elder boys return to Clearwater, Texas for their Mother's funeral. John the eldest is a well known gunfighter and trouble follows him wherever he goes. The boys try to get back their ranch from the towns gunsmith who won it from their father in a card game with which he was shortly murdered there after but not before getting through the troubles that come with the Elders name
Dusty Gardner, and other Texas ranchers, are driving a herd of cattle to Abilene, Kansas along the Chisholm Trail. Desperate need of water takes them to the Turner ranch, where Belle Turner demands exorbitant prices for the water. Dusty learns that Belle is also trying to oust Mary Lee and Montana Smith from the trading post Mary operates. The sheriff sides with Belle following a fight between the two women. Belle knows there is artesian springs under the land the trading post occupies and intends to get the property by any means.
Somewhere in Australia in the early 20th century outback, an Aboriginal man is accused of murdering a white woman. Three white men are on a mission to capture him with the help of an experienced Indigenous man.
A former Union Army officer plans to sell out to Anchor Ranch and move east with his fiancée, but the low price offered by Anchor's crippled owner and the outfit's bullying tactics make him reconsider. When one of his hands is murdered he decides to stay and fight, utilizing his war experience. Not all is well at Anchor with the owner's wife carrying on with his brother who also has a Mexican woman in town.